By Kelsey Sicker, MD Candidate, Class of 2019 // Edited by Michael Barrie, MD OSU EM Attending
Medicine is a constantly evolving field, with new therapies, preventive strategies, and understandings of disease pathology rapidly growing. As part of this evolution, vaccinations have become key to modern preventive medicine for children and have had a great impact on childhood morbidity and mortality.
With the implementation of universal vaccination recommendations, what long term effects have we seen on the epidemiology of epiglottitis?
Author: Sandy Brundage (OSU Medical Student Class of 2019) // Editor: Michael Barrie (OSU EM Assistant Professor)
A 56-year old woman presented to the ED for acute onset of shortness of breath with unilateral left leg swelling. PMH significant for a total knee replacement five days ago. Current medications include aspirin, lisinopril, metformin, labetalol and enoxaparin. CBC comes back with a platelet count of 30,000. Upon reviewing her chart, you notice that her platelet count prior to the surgery was 250,000. A lower extremity doppler confirms an acute deep venous thrombosis.
What is contributing to the development of thrombosis despite her medications and thrombocytopenia?